CARNOSINE
Carnosine is a dipeptide formed from two amino acids, beta-alanine and L-histidine, naturally found abundantly in nerve and muscle cells. Carnosine has been shown to rejuvenate cells, supply advanced brain cell and brain chemistry support and provide skin, nerve and muscle cell protection.
Carnosine is one of the best known glycation anti-aging fighters the body naturally produces, as it modulates protein formation of protein carbonyls, the prime maker of protein health. It is a powerful anti-oxidant, able to quench free radicals and prevent cross-linking of proteins. It inhibits damaged proteins from harming healthy proteins.
Supplementing carnosine may be an effective way to slow aging and prevent free radical damage. Add 1/4 teaspoon to a morning breakfast shake (or water or food) daily.
Beta-Alanine (Carnosine); lactic acid buffering agent.
Apparently supplementing beta-alanine is more effective at raising serum carnosine levels than supplementing l-carnosine itself. Carnosine is an effective acid buffering agent, and thus beta-alanine supplementation may prove to be an excellent way to stimulate new muscle fiber recruitment by allowing us to work through our normal lactic acid threshold. There is also word that because beta-alanine buffers lactic acid, combined with the fact that creatine is not effective in an acidic environment, supplementation may support optimal creatine effectiveness.
Functions
o Carnosine is capable of both enhancing cell function and stopping cell damage from occurring (due to beta amyloid, which is found in the brains of those with Alzheimer's disease). It assists in the chelation of ionic metals and the elimination of toxins from inside of the body. It can boost the immune system. It also can help with the sense of smell.
Glycosylation
o Carnosine is also capable of preventing glycosylation from happening. Glycosylation is a kind of enzymatic procedure that connects DNA molecules and proteins, due to sugar aldehydes encountering with the amino acids of the protein molecule. Preventing glycosylation is helpful for various medical conditions, including eye cataracts, kidney failure, certain skin conditions, diabetes and neuropathy.
Lactic Acid
o Carnosine is also capable of obstructing the accumulation of excess lactic acid in the body. Lactic acid triggers muscle pain after sessions of intense exercise. If this nutritional supplement is taken both before and after rigorous exercise sessions, it is possible that carnosine could decrease (and sometimes even entirely eliminate) this pain.
Eye Drops
o Carnosine is also used to help with senile cataracts. Senile cataracts occur in elderly individuals. They are the most common variety of cataracts, and generally happen with persons over 60 years old. They often cause complete vision loss. Carnosine eye drops work to both deconstruct and inhibit cross-linking of proteins.
Dosage
o Individuals are generally advised to take between 100mg and 300mg of carnosine every day. No more than 600mg should be taken in one day. Taking more than the recommended dosage amount of this nutritional supplement could lead to the undesirable side effect of muscle twitching.
o Overall Benefits:
o * Maintain a balanced pH in muscle when exercise is intense.
o * Potent Antioxidant
o * Keeps muscular vitality by increasing strength
o * Inhibits cell damage caused by alcohol
o * Heavy Metal chelating agent, specially for copper and zinc
o * Prevents carboxylation and glycosylation of cell proteins
o * By preventing molecule modification, it maintains functionality under stress conditions
o * Protects the proteasomes which take care of uneeded or damaged protein inside the cell
o * Acts as a neurotransmitter
CARNOSINE can also be benefitial in:
· Neurologic Degeneration such as Alzheimer, Parkinson, Epilepsy, Depression, Esquizofrenia, Dementia, Apoplexy attacks
· Autism, dyslexia, dyspraxia, Tourette’s Syndrome, Asperger Syndrome
· Overall aging
· Cataracts
· Formation of glycosidic radicals (AGE’s)
· Accumulation of damaged proteins
· Muscular atrophy
· Apoplexy
· Cardiovascular diseases
· Diabetes and its complications
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